jscreen’s Partnership With Colorectal Cancer Alliance
The Colorectal Cancer Alliance is fiercely determined to end colon and rectal cancers within our lifetime. jscreen® shares the belief that everyone deserves access to testing that can protect themselves and their families from devastating genetic diseases.
Hereditary risk for colon cancer can pass through a family for generations without an obvious pattern. Genetic testing can help give you clear, direct answers that you can act on.
The Two Main Hereditary Colon Cancer Syndromes
Most hereditary colon cancers fall into one of two well understood categories. Both are identifiable through genetic testing and have clear management options when caught early.
Who Should Consider Hereditary Colon Cancer Testing?
Family History of Colon Cancer
If a parent, sibling, or child has had colon cancer, especially at a young age, an inherited gene change that increases cancer risk may be involved and hereditary cancer genetic testing is recommended.
Early Age at Diagnosis in the Family
Colorectal cancer diagnosed before age 50, in you or a family member, is a strong sign of the possibility of a hereditary syndrome like Lynch syndrome that increases cancer risk. Genetic testing can identify your inherited risk.
Multiple Family Members with Colon Cancer
Two or more close relatives with colorectal cancer, especially across more than one generation, suggests an inherited cause that a comprehensive hereditary test can help identify.
Personal Colorectal Cancer Diagnosis
If you've been diagnosed with colon cancer, genetic testing can clarify whether an inherited syndrome is involved, which can affect your treatment and help protect your family members.
History of Uterine or Ovarian Cancer in the Family
Lynch syndrome raises the risk of uterine,ovarian and stomach cancers alongside colorectal cancer. A family history of these cancers is a strong indicator that genetic testing could be valuable.
Multiple Colon Polyps
Developing many colon polyps at a young age can be a sign of FAP or other hereditary polyposis syndromes, which may be detectable through genetic testing.
Genetic Testing That Fits Your Needs
The health of your family depends on it
jscreen is a national genetic screening and education program offering access to comprehensive, at-home testing and genetic counseling.
Learn about hereditary cancer testing and find out what is right for you.
Hereditary Cancer Testing
Why
Results are actionable and can be used for cancer prevention, early detection, and treatment.
What
jscreen is a national non-profit that offers access to comprehensive hereditary cancer testing. This test includes genes associated with Lynch syndrome (MLH1, MSH2, MSH6, PMS2, and EPCAM), BRCA1/2 and more than 60 other cancer predisposition genes. A genetic counselor reviews every case at intake and helps patients understand their results and take actionable next steps.
Who
This cancer test is designed for anyone who wants to understand their inherited cancer risk, and it works for people of all ancestries. It is particularly valuable for people with a personal history of cancer; people with a family history of cancer, especially at a young age; people with multiple relatives affected by the same or related cancers; and people of Ashkenazi Jewish ancestry due to their higher rates of certain mutations. While the test is available starting at age 18, jscreen typically recommends waiting until around age 25, depending on family history and other risk factors.
Why Genetic Testing Matters
A hereditary cancer test looks for inherited variants that raise your risk of cancer, giving you and your doctor real information to act on together. A positive result opens up options like risk-reducing surgeries, targeted therapies, and family planning support. A negative result, which means no pathogenic variants were found in the genes tested, may mean risk is no higher than average population risk, which can bring peace of mind to many people.
Actionable results
Family Impact
Early Detection Advantage
Genetic Counseling Included
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Four Easy Steps to Access Genetic Screening from Home
Order Your Kit
Register online and receive a saliva collection kit shipped directly to your home within a few days.
Collect Your Sample
Provide a simple saliva sample at home, following the easy step-by-step instructions included in your kit.
Lab Analysis
Your sample is analyzed at a CLIA-accredited laboratory using advanced sequencing technology across the full gene panel.
Receive Results
Receive your results within 3 to 4 weeks. You can choose to schedule a complimentary consultation with a certified genetic counselor to review your findings.