jscreen’s Partnership with No Stomach For Cancer

No Stomach For Cancer works to prevent and treat stomach cancer through research, education, and advocacy. jscreen® is a national non-profit that shares the belief that everyone deserves access to testing that can protect themselves and their families from devastating genetic diseases.

Hereditary risk for stomach cancer can pass through a family for generations without an obvious pattern. Some inherited syndromes also increase the risk for breast cancer. Genetic testing gives you clear, direct answers you can act on.

Genetic Testing That Fits Your Needs

The health of your family depends on it

jscreen is a national genetic screening and education program offering access to comprehensive, at-home testing and genetic counseling.

Learn about hereditary cancer testing and find out what is right for you.

Hereditary Cancer Testing

Learn your risk for hereditary cancer, in a single test.

Why

Results are actionable and can be used for cancer prevention, early detection, and treatment.

What

jscreen is a national non-profit that offers access to comprehensive hereditary cancer testing. This test includes CDH1, CTNNA1, BRCA1/2, Lynch syndrome, and more than 60 other cancer predisposition genes. A genetic counselor reviews every case at intake and helps patients understand their results and take actionable next steps.

Who

This cancer test is designed for anyone who wants to understand their inherited cancer risk, and it works for people of all ancestries. It is particularly valuable for people with a personal history of cancer; people with a family history of cancer, especially at a young age; people with multiple relatives affected by the same or related cancers; and people of Ashkenazi Jewish ancestry due to their higher rates of certain mutations. While the test is available starting at age 18, jscreen typically recommends waiting until around age 25, depending on family history and other risk factors.

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Why Genetic Testing Matters

A hereditary cancer test looks for inherited variants that raise your risk of cancer, giving you and your doctor real information to act on together. A positive result opens up options like risk-reducing surgeries, targeted therapies, and family planning support. A negative result, which means no pathogenic variants were found in the genes tested, may mean risk is no higher than average population risk, which can bring peace of mind to many people.

Actionable results

Clear, laboratory-interpreted findings with guidance on next steps.

Family Impact

Understanding your genetics helps protect siblings, children, and other relatives who may share your risk.

Early Detection Advantage

Knowing your inherited cancer risks enables proactive screening strategies that can help save lives.

Genetic Counseling Included

Every jscreen result includes access to a board-certified genetic counselor who will walk you through your report, answer your questions, and coordinate care recommendations with your physician.

Learn More about Genetic Testing

Four Easy Steps to Access Genetic Screening from Home

Order Your Kit

Collect Your Sample

Provide a simple saliva sample at home, following the easy step-by-step instructions included in your kit.

Lab Analysis

Your sample is analyzed at a CLIA-accredited laboratory using advanced sequencing technology across the full gene panel.

Receive Results

Receive your results within 3 to 4 weeks. You can choose to schedule a complimentary consultation with a certified genetic counselor to review your findings.

Costs and Insurance Coverage

jscreen was established on a simple but deeply held belief: that everyone deserves access to testing that can protect themselves and their families from devastating genetic diseases. We’re committed to working with you to ensure cost is never a barrier.

Insurance Billing

Most commercial insurance plans cover hereditary cancer testing for individuals who meet criteria based on their racial or ethnic background, personal history, or family history. You will receive a personalized cost estimate from our lab partner. Your final cost depends on your family history and specific insurance plan. Our care navigators are here to help you work through the process and connect you with our financial assistance programs when needed.

Self-Pay Option

Prefer not to use insurance? jscreen offers a straightforward, competitive self-pay rate of $249, plus the upfront fee of $49, for a total of $298. This covers lab testing fees, physician review and test ordering, and access to our genetic counselors and care navigators throughout the testing process.

If cost is a barrier to testing, financial assistance for lab fees may be available through No Stomach For Cancer.

Gene Table: Hereditary Stomach Cancer

The full gene list is available here. Results are reviewed by board certified genetic counselors. This is not a complete list of genes that should be tested when personal and/or family history features are present.

Gene

Disease

CDH1

The gene associated with hereditary diffuse gastric cancer syndrome. Carriers face up to an 80% lifetime risk of stomach cancer, along with a higher risk of lobular breast cancer in female carriers.¹

MLH1

A Lynch syndrome gene. Carriers face an 8–16% lifetime risk of stomach cancer, along with a significantly higher colorectal and uterine cancer risk.²

CTNNA1

Diffuse gastric cancer (DGC) is the most common manifestation in germline CTNNA1 variant carriers, with one study estimating a 49–57% lifetime risk by age 80.³

MSH2

A Lynch syndrome gene with a stomach cancer risk similar to MLH1, at 8–16%.²

MSH6

A Lynch syndrome gene with a comparatively lower stomach cancer risk than MLH1 or MSH2, though still clinically relevant.²

STK11

The gene behind Peutz-Jeghers syndrome, which causes polyps throughout the digestive tract along with dark spots on the lips and mouth. Carriers face up to a 29% lifetime risk of stomach cancer.⁴

SMAD4 BMPR1A

These genes are associated with juvenile polyposis syndrome, leading to multiple polyps in the stomach and intestines. Carriers face up to a 21% lifetime risk of stomach cancer.⁴

APC

Certain changes in the promoter region of the APC gene cause gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS), marked by widespread stomach polyps and a stomach cancer risk between 7% and 30%.⁵

Stomach cancer may be preventable if you know your risk.

Understanding your risk is one of the most proactive steps you can take for your health, and your family's. Thousands of people have already taken that step. You can too.

Get Started Today